Ankh of Life
|Gives you 1 max health every time you open a chest.
Unlock: Defeat the tier 5 boss. (Needs confirmation)
Stacking: More health per chest opened.
|Killing enemies gives a very small amount of max health.
Stacking: Higher chance to give the player more max health when killing an enemy.
|Melee attacks sap health from enemies hit.
Stacking: More health is drained per hit.
|Bullets randomly explode, dealing damage in a small radius.
Unlock: Reach depth 5,000 without taking damage while equipped with TNT Sling.
Stacking: Bigger explosions, more damage.
|Randomly punch enemies with great force.
Stacking: Fists do more damage (8 damage per stack). May also increase knockback.
|Grants an additional jump.
Stacking: One extra jump per stack.
|Each stack will instantly shoot a second round of bullets.
Unlock: Collect 2 or more Spreadshot with the Nailgun
Stacking: More bullets!
Cluster of Iron
|Bigger bullets, more damage.
Stacking: further increased bullet size and damage.
|Gives you an additional melee weapon, increasing damage and dig speed.
Stacking: Adds another melee weapon each time.
|Leaves a trail of fire.
Stacking: Trail gets taller and does more damage.
Heart of Belial
|Regenerates health over time.
Unlock: Recover 1000 HP in a single run with Rex's passive ability.
Stacking: Regenerates health faster.
|Increases accuracy and crit chance. Adds a laser sight to your weapon.
Stacking: Adds a bigger chance of getting a crit.
|Bolsters melee attack speed.
Stacking: Makes swinging even faster.
Pylon of Frost
|Freezes enemies in their tracks.
Stacking: Increases slow.
|Periodically throw knives.
Stacking: Knives are thrown more often.
Unlock: Defeat Giga Mechworm.
Stacking: Runs even faster.
|Randomly fires a missile.
Stacking: More missiles more often.
|Increases the number of projectiles your gun fires. also seems to decrease shot size and damage slightly, this effect doesn't seem to stack, also renders growth battery useless.
Stacking: More projectiles are fired each stack.
|Attacks reduce armor.
Stacking: More armor reduction.
|Strikes nearby enemies with green shards.
Stacking: Shards do more damage (3 per stack) and travel farther.
|Increases critical hit damage.
Stacking: Increases crit damage further.
|Adds a poison effect when you hit a enemy with your projectiles.
Stacking: Adds more damage per tick.
|Emits cloud of poison on impact.
Stacking: Increases cloud size and poison damage.
Bullets have a chance to shock nearby enemies.
Unlock: Kill an Electric Elite By knocking it off the edge.
Stacking: Higher chance of shocking.
|Shoots a sword (where you're aiming at) when at full health and using melee.
Stacking: Sword does more damage.
|A shield that explodes after taking damage.
Stacking: Shield absorbs more damage before exploding, deals more damage and has a shorter cooldown.
|Chance to instantly kill enemy on critical hit. currently tends to lag the game when you hit a enemy with a sawblade CRITICAL.
Stacking: Higher chance to kill.
|Plagues enemies shot with infection that spreads to other enemies.
Stacking: Higher chance to plague.
|Randomly unleashes an explosive swarm of beetles on impact.
Bomb Squad Armor
|Increases armor and reflects damage.
Stacking: Increases armor further.
|Destroyed terrain can sometimes spawn health.
Stacking: Higher chance of health spawning.
Black Hole Box
|Increases magnetic power.
Stacking: Increases magnetic power further.
Tome of Secrets
Increases chance of random powerup drops.
Unlock: Earn all golden weapons.
Stacking: Higher chance of drops.
Has a chance to throw a grenade that stuns enemies
Unlock: survive arena mode for 3 minutes
Critical hits inflict enemies with a paralyzing curse.
Currently bugged and causes you to take damage over time
Stacking: increases stun duration
Stuns every enemy when you level up.
Stacking: increases stun duration
|Giga Drill Bit||
Increases digging power.
Stacking: further increases digging power.
Creates a ghostly clone when you take damage. Clone appears as a transparent outline of your character and shoots several projectiles that seek the closest enemy.
Stacking: Increases number of projectiles spawned.
A serum that increases gem discovery.
Unlock: Kill a wall golem. (Needs confirmation)
Stacking: further increases amount of gems dropped by enemies.
Charges your bullets while not shooting.
Reduces the cost of chests.
Stacking: further reduces cost of chests.
Increases damage based on gems held.
Unlocked by having 20000 gold.
Dying enemies release vengeful spirits.
Picking up gems grants health
Some enemies explode on death.
Large gems deal damage to enemies
|Clump of Moss||
Critical hits grant health.
Stacking: more health gained per crit.